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It's a double whammy. At the same time the prefrontal cortex is getting weaker and more primitive, the brain circuits that generate emotion like fear are getting stronger, you start seeing the world as harmful even when it's not.

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    Who Said, “We have nothing to fear, but fear itself”?
    A Lyndon B. Johnson
    B Evel Knievel
    C John F. Kennedy
    D Franklin D. Roosevelt