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Nicole Lurie is an American physician, professor of medicine, and public health official. During the administration of President Barack Obama, she was Assistant Secretary for Preparedness and Response (ASPR) at the United States Department of Health and Human Services (HHS) from 2009 through the end of the president's second term. The mission of the Office of the Assistant Secretary for Preparedness and Response is to "lead the nation in preventing, responding to and recovering from the adverse health effects of public health emergencies and disasters, ranging from hurricanes to bioterrorism."

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