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The vast majority of treatments for Crohn’s and ulcerative colitis are completely safe for a female to take when she is conceiving and equally safe during pregnancy and breastfeeding, for patients who are acutely ill, however, from their Crohn’s or ulcerative colitis, there may be multiple good reasons not to have children including depression, malnutrition, amenorrhea (lack of menstruation), and general poor quality of life.