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In my experience as a clinician, as well as some studies that have been undertaken, many of the individuals who are family members have symptoms, though they may not have complained of those symptoms to their doctors, sometimes because they did not realize they were an abnormality and sometimes because they were never asked, in that circumstance, I often find in my practice that patients who go on a gluten-free diet, who themselves did not even appreciate the symptoms, often feel better.