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Drugs for HIV have now been developed that have little interaction with many chemotherapy agents and The HIV-infected patients can be switched easily from one class of antiretroviral treatment to another without too much difficulty to avoid drug interactions, those of us oncologists who are knowledgeable about both HIV and cancer can easily manage most HIV cancer patients, and we recommend that HIV patients with cancer be treated as aggressively and with the same treatment as we would use in our non-HIV patients.