The Big Bang Theory2007

Penny:
OK, I get it. Not all the jibber jabber in the middle, but I know what it's like to put your heart and soul into something and get nothing out of it.

Sheldon Cooper:
You mean your acting career.

Penny:
No.

Sheldon Cooper:
Your relationship with Leonard.

Penny:
No.

Sheldon Cooper:
Your failed attempt to go back to college.

Penny:
NO! I'm saying you and string theory sound like a relationship and I know what it's like to be in one and realize it's never going to turn out the way you want.

Sheldon Cooper:
I said Leonard. You said no.

Penny:
I'm talking about other guys.

Sheldon Cooper:
OK. Well. What do you do?

Penny:
You have to have the courage to end the relationship. You know, break it off, shake hands, walk away.