Batman: Arkham City2011

The Joker:
Quick, the cure! What are you waiting for? Come on! I killed your girlfriend, poisoned Gotham, and hell, it's not even breakfast. But so what? We all know you'll save me.

Batman:
Every decision you've ever made ends in death and misery. People die. I stop you. You'll just break out and do it again.

The Joker:
Think of it as a running gag...

[the Joker leaps out and stabs Batman in the shoulder, causing him to drop the vial containing the cure, shattering it]

The Joker:
Nooooo!

[Batman pulls out the knife while the Joker drops to the floor and begins desperately trying to grab some of the cure]

The Joker:
Are you happy now?

Batman:
You want to know something funny? Even after everything you've done... I would have saved you.

The Joker:
[laughs, coughs] That actually is... pretty funny...

The Joker:
[starts laughing and coughing, then gasping for air and finally dies, smiling]