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Piebaldism is actually a disease, it's caused by cells in the early embryo failing to migrate correctly.... failing to get to the right place. The cells which we're interested in, that cause piebaldism, are called melanocytes and they're responsible for pigmentation of hair and of the skin. These cells start at the back of the embryo and they try to migrate round through the skin and cover the whole of the( embryo's) skin. When they fail to do that properly you tend to get regions of skin or hair which are lacking in pigment, often regions at the front of an animal. This is common in cats...... tuxedo cats, and it's also common in horses and pigs and even in humans.

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