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We need to pinpoint exactly how the splicing factors are causing the cells to rejuvenate, and identify the key points where we could intervene to stop them declining as we age, or to restore them once the damage is done, we’re now addressing why the splicing factors get switched off as we age, what the downstream consequences of this are for the regulation of our genes and the behavior of our cells, and also to identify new ways by which we might be able to intervene in these processes.

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