Stargate Atlantis, Season 4

Lt. Col. Sheppard:
[Typing in Rodney's password, who thinks Sheppard can't remember it] 16431879196842. See, it doesn't take a genius.

Teyla:
I-it doesn't?

Lt. Col. Sheppard:
1643 is the year Isaac Newton was born. 1879, Einstein. And 1968...

Teyla:
The year Rodney was born.

Lt. Col. Sheppard:
Never underestimate the size of that man's ego.

Teyla:
Weren't there other numbers?

Lt. Col. Sheppard:
42.

Teyla:
What is that?

Lt. Col. Sheppard:
It's the ultimate answer to the great question of life, the universe and everything.

[Teyla stares at him blankly.]