Supernatural, Season 4

Dean:
Well, I dunno when it happened. Maybe when I was in Hell. Maybe when I was starin' right at you. But the Sam I knew; he's gone.

Sam:
That so.

Dean:
And it's not the demon blood or the psychic crap...it's the little stuff. The lies. The secrets.

Sam:
Oh yeah, what secrets?

Dean:
Your phone calls to Ruby, for one.

Sam:
So I need your say-so to make a phone call?

Dean:
That's the point. You're hiding things from me. What else aren't you telling me?

Sam:
None of your business.

Dean:
See what I mean? We used to be in this together. We used to have each other's backs!

Sam:
Okay, fine, you wanna know why I didn't tell you about Ruby? And how we're hunting down Lilith? Because you're too weak to go after her, Dean. You're holding me back. I'm a better hunter than you are. Stronger, smarter; I can take out demons you're too scared to go near.

Dean:
That's crap.

Sam:
You're too busy sitting around feeling sorry for yourself, whining about all the souls you tortured in Hell, boo-hoo... You're not standin' in my way, anymore!