Supernatural, Season 4

Castiel:
Are you alright?

Dean:
No thanks to you.

Castiel:
You need to be more careful.

Dean:
You need to learn how to manage a damn Devil's Trap.

Castiel:
That's not what I mean. Uriel is dead.

Dean:
Was it the demons?

Castiel:
It was disobedience. He was workin' against us.

Dean:
Is it true? Did I break the first seal? Did I start all this?

Castiel:
Yes. When we discovered Lilith's plan for you, we laid siege to Hell. And we fought our way to get to you before you -

Dean:
Jump-started the apocalypse.

Castiel:
We were too late.

Dean:
Why didn't you just leave me there then?

Castiel:
It's not blame that falls on you, Dean. It's fate. The righteous man who begins it is the only one who can finish it. You have to stop it.

Dean:
Lucifer? The apocalypse? What does that mean? Hey! Don't you go disappearing on me you son-of-a-bitch. What does that mean?

Castiel:
I don't know.

Dean:
Bull!

Castiel:
I don't. Dean, they don't tell me much. I know our fate rests with you.

Dean:
Well, then you guys are screwed. I can't do it, Cas. It's too big. Alastair was right. I'm not all here, I'm not st-I'm not strong enough. Well, I guess I'm not the man either of our dads wanted me to be. Find someone else. It's not me.