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'[Howard enters Leonard's laboratory to mock him for his unsuccessful date the previous evening]Howard: Hey.Leonard: [handing him a pair of glasses] Laser.Howard: Had a great night last night. I don't like to kiss and tell, but... [puts glasses on] somebody made it to eighth base!Leonard: The hell is eighth base?Howard: Seventh base with shirt off. Well... My shirt. How'd things go with Penny?Leonard: [sarcastically] Oh, yes... Couldn't be better.[He fires up the laser, igniting a Cylon action figure in its path and startling Howard]Howard: Are we taking our relationship frustrations out on innocent Cylons?Leonard: [extinguishing the fire] It's not just Cylons. Superman's next.Howard: Alright. I was gonna try to squeeze in a little more mocking before lunch, but I can come back later, when you don't have a high-power weapon.Leonard: How can I go out with a woman who believes in psychics?Howard: Hey, I once dated a girl who believed she was abducted by aliens.Leonard: And that didn't bother you?Howard: Au contraire. It meant she was gullible and open to a little probing.Leonard: What am I supposed to do, pretend I believe something I don't whenever I'm with Penny?Howard: Hey I'm sure Penny fakes all kinds of things when she's with you.Leonard: Do me a favor. [points to the area in front of the laser] lean over and put your head right here.Howard: Let me show you another way to look at this. [Draws a large box on a dry-erase board] Here we have the universe of all women. [Draws one large circle inside the box] These are the ones you want to sleep with. [Draws an equal-size circle slightly intersecting the first] These are the women who believe exactly what you believe. [Draws a very small circle at bottom of the intersection] These are the women who would be willing to sleep with you. Right there at the little triple intersection is your ideal mate. Odds are she's a short physicist with low self-esteem who lives in a government research facility in China.Leonard: What's your point? In order to keep having a sexual relationship with Penny, I have to give up everything I believe in, my intellectual integrity, the very nature of who I am? I can't do that, Howard.Howard: I respect that. [takes Leonard's hand and dots his palm with the marker]Leonard: What is that?Howard: Your new girlfriend. Have fun tonight.

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    In which movie does this quote appear: "Houston, we have a problem"?
    A Conquest of Space
    B 2001: A Space Odyssey
    C Apollo 13
    D Star Trek Generations