CSI: Crime Scene Investigation, Season 12

Nick (to Catherine):
What are you saying?

Catherine:
That I've been offered another job. With the FBI. I've decided to take it.

Sara:
When?

Catherine:
Well, it's effective immediately. I tendered my resignation. For real this time. You are all family which is why this is the hardest decision I've ever made. I mean, how could I leave this place? How could I leave all of you? But not only are you in great hands, but you are a rock-solid, bad-ass team of criminalists and don't ever forget it.

Nick:
We all just love you, Catherine and, you know, even though you're leaving, you'll always be here with us, always.