Grey's Anatomy, Season 4

Meredith:
[voiceover] We go into medicine because we want to save lives. We go into medicine because we want to do good. We go into medicine for the rush, for the high, for the ride. But, what we remember at the end of most days are the losses. What we lay awake at night replaying is the pain we caused or failed to cure. The lives we ruined or failed to save. So the experience of practicing medicine rarely resembles the goal. The experience too often is ass backwards and upside down.