Grey's Anatomy, Season 6

Izzie:
Get up. I mean it get up. Get up! Now go get a life.

Amanda:
I can't.

Izzie:
George was a surgeon. He had a purpose he wanted to save lives and now he doesn't get the chance. Now he doesn't get the chance to do anything anymore. But you do. You could go to medical school, you know. You could hang out with your freaking friends, I don't care what you do. Just go do something with your life because you have one. You lived. You lived and George didn't and I know... I know... that that feels horrible and shocking and terrifying but you lived. So go live your freaking life.

Amanda:
I don't know how.

Izzie:
Nobody does. Nobody knows how. But god have enough respect for George to figure it out cos if I see you sitting on this bench ever again I will kick your ass from here to Sunday.