House, Season 8

Wilson:
It's pathetic. I'm pathetic. An oncologist with cancer. Of all the things that could be killing me...It's like the universe is giving me the big middle finger.

House:
The universe doesn't care--

Wilson:
Why me? I'm always telling my patients not to torture themselves, because there's no answer.

House:
Sound advice.

Wilson:
It's cruel advice. They were just trying to make sense of what was happening to them, and I'm there telling them not to bother? I should have spent my life being more like you. Should have been a manipulative, self-centered, narcissistic ass who brought misery to everything and everyone in his life.

House:
You'd still have cancer.

Wilson:
Yeah! But at least I'd feel like I deserved it.