Star Trek: Deep Space Nine, Season 5

[In response to Maquis terrorist attacks, Sisko has detonated biological weapons in the atmosphere of one of their colony worlds]

Michael Eddington:
[aghast]Do you realise what you've done?

Sisko:
I've only just begun. I'm going to eliminate every Maquis colony in the DMZ.

Eddington:
You're talking about turning hundreds of thousands of people into homeless refugees!

Sisko:
That's right. When you attacked the Malinche, you proved one thing; that the Maquis have become an intolerable threat to the security of the Federation, and I am going to eliminate that threat.

Eddington:
But think about those people you saw in the caves, huddled and starving. They didn't attack the Malinche.

Sisko:
You should have thought about that before you attacked a Federation starship.