American Dad!, Season 1

[Francine is preparing to kill George Clooney with an axe]

Francine:
Well, I'd better run. George Clooney's head is about to have a big opening weekend.

Stan:
Wait! I've gone along with you on this whole thing, no questions asked, but now I've gotta know. What the hell, Francine? What is this really about? I mean, I hate Susan Sarandon, but you don't see me cutting off my hand. I just cut my hair different for a while.

Francine:
What is this about? Just look at that f***er with cucumbers on his eyes! Not a care in the world. No making school lunches, no grocery shopping, no cleaning the house, no one depending on him all the time!

Stan:
Oh, God. This isn't about some unfulfilled dream. You're having a midlife crisis and you're taking it out on a future senator from California!

Francine:
Midlife crisis? Wait. Future senator? Oh, I will f***ing chop his head in two!

Stan:
Francine, don't you see? Sure, Clooney has no cares, no one that depends on him, but... he has no one that depends on him. But you, you have a family: A son, a daughter...

Francine:
...and a husband who took a sabbatical from work, moved to Prague, and hired mercenaries to help his wife seduce another man! You probably would have let me sleep with him.

Stan:
Of course! I assumed you did!

[both laugh]

Francine:
I'm the luckiest girl in the world.

[both turn to Clooney]

Francine:
You know, I actually feel sorry for him. He'll never know this kind of happiness. Let's go home.