Supernatural, Season 5

Sam:
The wraith-

Dean:
What about her?

Sam:
She was right.

Dean:
No, she wasn't. She's dead, okay? Let's hit the road. I need a drink...or twelve.

Sam:
Most of the time I can hide it, but I am angry. I'm mad at everything. I used to be mad at you and dad, then Lilith, now it's Lucifer. And I make excuses: I blame Ruby, or the demon blood, but-but it's not their fault, it's not them, it's me. It's inside me. I'm mad all the time, and I don't know why.

Dean:
Stop. Stop it. So what if you are? What are you gonna take a leave of absence? You gonna say yes to Lucifer? What?

Sam:
No, of course not.

Dean:
Exactly. And that's exactly what you're going to do: you're going to take all that crap, and you're gonna bury it. You're gonna forget about it, because that's how we keep going.