The Big Bang Theory, Season 6

Sheldon:
You may find this hard to believe, but I didn't have any friends growing up.

Arthur Jeffries:
You know, I get that.

Sheldon:
But, um, I did have you. And every day at 4 o'clock you'd come to my house on channel 68 and we'd do science together. If it hadn't been for you, who knows what would have become of me. You know, instead of a world class physicist I could have wound up a hobo … or a surgeon.

Leonard:
I bet there are important discoveries made every day because you inspired millions of kids to pursue science. In a way their discoveries are your discoveries.

Sheldon:
It's true. A generation of young scientists are standing on your shoulders.

Arthur:
Well thanks, thanks, you guys. That means a lot.

Leonard:
It's important you know how much mean to us.