Agents of S.H.I.E.L.D., Season 4

Simmons:
We're going to save them.

Fitz:
What if we can't? What if May suffers from permanent cognitive dysfunction or cerebral atrophy? Or she dies?

Simmons:
Fitz...

Fitz:
We don't know the adverse effects this could have on her brain. I did it to her. AIDA, the Framework, my fingerprints are all over these murder weapons. Mack was right.

Simmons:
Mack was right, you do need to think about the implications of the things you create. But just because someone uses your ideas for evil does not make it your fault for creating it in the first place. You make things from the genius of your mind and the goodness of your heart, to help people! Don't let Radcliffe's actions corrupt that! You are not responsible for the twisted things he's done. Wrongs have been committed, now we make them right. Together.